Showing chemical card for glutamate-1-semialdehyde (CFc000337819)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:31:52 UTC
Chemfont ID
CFc000337819
Molecule Identification
Common Name
glutamate-1-semialdehyde
Definition
Glutamate-1-semialdehyde, also known as (S)-4-amino-5-oxopentanoate or L-glutamic acid 1-semialdehyde, belongs to gamma amino acids and derivatives class of compounds. Those are amino acids having a (-NH2) group attached to the gamma carbon atom. Glutamate-1-semialdehyde is soluble (in water) and a weakly acidic compound (based on its pKa). Glutamate-1-semialdehyde can be found in a number of food items such as endive, radish, celery leaves, and welsh onion, which makes glutamate-1-semialdehyde a potential biomarker for the consumption of these food products. Glutamate-1-semialdehyde may be a unique E.coli metabolite. Glutamate-1-semialdehyde is a molecule formed from by the reduction of tRNA bound glutamate, catalyzed by glutamyl-tRNA reductase. It is isomerized by glutamate-1-semialdehyde 2,1-aminomutase to give aminolevulinic acid in the biosynthesis of porphyrins, including heme and chlorophyll .
Belongs to the class of organic compounds known as gamma amino acids and derivatives. These are amino acids having a (-NH2) group attached to the gamma carbon atom.
