| Definition | Anthranilic acid, also known as 2-aminobenzoic acid or anthranilate, is a member of the class of compounds known as aminobenzoic acids. Aminobenzoic acids are benzoic acids containing an amine group attached to the benzene moiety. Anthranilic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa). Anthranilic acid can be found in a number of food items such as tinda, soursop, swiss chard, and celery leaves, which makes anthranilic acid a potential biomarker for the consumption of these food products. Anthranilic acid can be found primarily in blood, cerebrospinal fluid (CSF), feces, and urine, as well as in human epidermis and fibroblasts tissues. Anthranilic acid exists in all living species, ranging from bacteria to humans. In humans, anthranilic acid is involved in the tryptophan metabolism. Anthranilic acid is formally rated as an unfounded non-carcinogenic (IARC 3) potentially toxic compound. Anthranilic acid (o-amino-benzoic acid, 2-aminobenzoic acid, 2-AA, 2AA, AA) is an aromatic acid with the formula C6H4(NH2)(CO2H). The molecule consists of a substituted benzene ring, hence is classed as aromatic, with two adjacent, or "ortho-" functional groups, a carboxylic acid and an amine. The compound is consequently amphoteric. In appearance, anthranilic acid is a white solid when pure, although commercial samples may appear yellow. It is sometimes referred to as vitamin L1 and has a sweetish taste. The anion [C6H4(NH2)(CO2)]−, obtained by the deprotonation of anthranilic acid, is called anthranilate . As a uremic toxin, this compound can cause uremic syndrome. Uremic syndrome may affect any part of the body and can cause nausea, vomiting, loss of appetite, and weight loss. It can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma. Abnormal bleeding, such as bleeding spontaneously or profusely from a very minor injury can also occur. Heart problems, such as an irregular heartbeat, inflammation in the sac that surrounds the heart (pericarditis), and increased pressure on the heart can be seen in patients with uremic syndrome. Shortness of breath from fluid buildup in the space between the lungs and the chest wall (pleural effusion) can also be present (T3DB). |
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| 2-Aminobenzoesaeure | ChEBI | | 2-Carboxyaniline | ChEBI | | O-Aminobenzoesaeure | ChEBI | | O-Aminobenzoic acid | ChEBI | | O-Carboxyaniline | ChEBI | | Vitamin L1 | ChEBI | | Anthranilic acid | Kegg | | 2-Aminobenzoate | Kegg | | O-Aminobenzoate | Generator | | Anthranilate | Generator | | Anthranilic acid, cadmium salt | HMDB | | Anthranilic acid, calcium (2:1) salt | HMDB | | Anthranilic acid, monolithium salt | HMDB | | Sodium anthranilate | HMDB | | Anthranilic acid, dihydrochloride | HMDB | | Anthranilic acid, hydrochloride | HMDB | | Anthranilic acid, monosodium salt | HMDB | | 1-Amino-2-carboxybenzene | HMDB | | 2-Amino-benzoate | HMDB | | 2-Amino-benzoic acid | HMDB | | 2-Aminophenylacetate | HMDB | | 2-Aminophenylacetic acid | HMDB | | Anthranate | HMDB | | Anthranic acid | HMDB | | Anthranilic acid GR | HMDB | | Carboxyaniline | HMDB | | H-2-Abz-OH | HMDB | | Kyselina anthranilova | HMDB | | Kyselina O-aminobenzoova | HMDB | | O-Amino-benzoate | HMDB | | O-Amino-benzoic acid | HMDB | | O-Anthranilate | HMDB | | O-Anthranilic acid | HMDB | | Ortho-amidobenzoate | HMDB | | Ortho-amidobenzoic acid | HMDB | | Ortho-aminobenzoate | HMDB | | Ortho-aminobenzoic acid | HMDB | | Vitamin L | HMDB |
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