Showing chemical card for 5-phosphoribosyl-N-formylglycineamidine (CFc000337658)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:31:35 UTC
Chemfont ID
CFc000337658
Molecule Identification
Common Name
5-phosphoribosyl-N-formylglycineamidine
Definition
Phosphoribosylformylglycineamidine, also known as 2-(formamido)-n1-(5-phospho-D-ribosyl)acetamidine or fgam, is a member of the class of compounds known as pentose phosphates. Pentose phosphates are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. Phosphoribosylformylglycineamidine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). Phosphoribosylformylglycineamidine can be found in a number of food items such as common salsify, butternut, jerusalem artichoke, and skunk currant, which makes phosphoribosylformylglycineamidine a potential biomarker for the consumption of these food products. Phosphoribosylformylglycineamidine exists in all living organisms, ranging from bacteria to humans. In humans, phosphoribosylformylglycineamidine is involved in few metabolic pathways, which include azathioprine action pathway, mercaptopurine action pathway, purine metabolism, and thioguanine action pathway. Phosphoribosylformylglycineamidine is also involved in several metabolic disorders, some of which include adenosine deaminase deficiency, aICA-Ribosiduria, gout or kelley-seegmiller syndrome, and xanthine dehydrogenase deficiency (xanthinuria).
Belongs to the class of organic compounds known as pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups.
