Showing chemical card for 3-hydroxypropionate (CFc000337581)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:31:27 UTC
Chemfont ID
CFc000337581
Molecule Identification
Common Name
3-hydroxypropionate
Definition
Hydroxypropionic acid, also known as 3-hydroxypropionate or hydracrylic acid, belongs to beta hydroxy acids and derivatives class of compounds. Those are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom. Hydroxypropionic acid is soluble (in water) and a weakly acidic compound (based on its pKa). Hydroxypropionic acid can be synthesized from propionic acid. Hydroxypropionic acid is also a parent compound for other transformation products, including but not limited to, beta-propiolactone, ascr#5, and 3-hydroxypropanoyl-CoA. Hydroxypropionic acid can be found in a number of food items such as apple, poppy, yam, and cupuaçu, which makes hydroxypropionic acid a potential biomarker for the consumption of these food products. Hydroxypropionic acid can be found primarily in blood, cerebrospinal fluid (CSF), feces, and urine. Hydroxypropionic acid exists in all living organisms, ranging from bacteria to humans. In humans, hydroxypropionic acid is involved in the propanoate metabolism. Hydroxypropionic acid is also involved in few metabolic disorders, which include malonic aciduria, malonyl-coa decarboxylase deficiency, and methylmalonic aciduria due to cobalamin-related disorders. Moreover, hydroxypropionic acid is found to be associated with biotinidase deficiency and propionic acidemia. Hydroxypropionic acid is a non-carcinogenic (not listed by IARC) potentially toxic compound. Hydroxypropanoic acid, or alternately hydroxypropionic acid, may refer to either of two isomeric chemical compounds: 3-Hydroxypropionic acid (hydracrylic acid) Lactic acid (2-hydroxypropanoic acid) . Chronically high levels of hydroxypropionic acid are associated with at least 5 inborn errors of metabolism including: Biotinidase deficiency, Malonic Aciduria, Methylmalonate Semialdehyde Dehydrogenase Deficiency, Methylmalonic Aciduria, Methylmalonic, Aciduria Due to Cobalamin-Related Disorders and Propionic acidemia (T3DB).
3D Structure for CFc000337581 (3-hydroxypropionate)
Synonyms
Value
Source
3-HYDROXY-propanoIC ACID
ChEBI
3-Hydroxypropanoic acid
ChEBI
beta-Hydroxypropionic acid
ChEBI
Hydracrylic acid
ChEBI
3-Hydroxypropionate
Kegg
3-Hydroxypropionic acid
Kegg
3-HYDROXY-propanoate
Generator
3-Hydroxypropanoate
Generator
b-Hydroxypropionate
Generator
b-Hydroxypropionic acid
Generator
beta-Hydroxypropionate
Generator
Β-hydroxypropionate
Generator
Β-hydroxypropionic acid
Generator
Hydracrylate
Generator
Hydroxypropionate
Generator
2-Deoxyglycerate
HMDB
2-Deoxyglyceric acid
HMDB
b-Lactate
HMDB
b-Lactic acid
HMDB
beta-Lactate
HMDB
beta-Lactic acid
HMDB
Ethylenelactate
HMDB
Ethylenelactic acid
HMDB
Chemical Formula
C3H6O3
Average Molecular Weight
90.0779
Monoisotopic Molecular Weight
90.031694058
IUPAC Name
3-hydroxypropanoic acid
Traditional Name
hydroxypropionic acid
CAS Registry Number
503-66-2
SMILES
OCCC(O)=O
InChI Identifier
InChI=1S/C3H6O3/c4-2-1-3(5)6/h4H,1-2H2,(H,5,6)
InChI Key
ALRHLSYJTWAHJZ-UHFFFAOYSA-N
Chemical Taxonomy
Description
Belongs to the class of organic compounds known as beta hydroxy acids and derivatives. Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.
