Showing chemical card for 1,3-bisphospho-D-glycerate (CFc000337466)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:31:15 UTC
Chemfont ID
CFc000337466
Molecule Identification
Common Name
1,3-bisphospho-D-glycerate
Definition
Glyceric acid 1,3-biphosphate, also known as 1,3-bisphospho-D-glycerate or 3-phospho-D-glyceroyl phosphate, belongs to the class of organic compounds known as acyl monophosphates. These are organic compounds containing a monophosphate linked to an acyl group. They have the general structure R-CO-P(O)(O)OH, R=H or organyl. The (R)-enantiomer of 3-phosphoglyceroyl dihydrogen phosphate. Glyceric acid 1,3-biphosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). Glyceric acid 1,3-biphosphate exists in all living species, ranging from bacteria to humans. Within humans, glyceric acid 1,3-biphosphate participates in a number of enzymatic reactions. In particular, glyceric acid 1,3-biphosphate can be biosynthesized from D-glyceraldehyde 3-phosphate; which is catalyzed by the enzyme glyceraldehyde-3-phosphate dehydrogenase. In addition, glyceric acid 1,3-biphosphate can be biosynthesized from 3-phosphoglyceric acid through the action of the enzyme pantothenate kinase 1. In humans, glyceric acid 1,3-biphosphate is involved in the metabolic disorder called the glycogen storage disease type 1A (gsd1a) or von gierke disease pathway. Outside of the human body, Glyceric acid 1,3-biphosphate has been detected, but not quantified in, several different foods, such as cherry tomato, jostaberries, canada blueberries, lovages, and mamey sapotes. This could make glyceric acid 1,3-biphosphate a potential biomarker for the consumption of these foods.
Belongs to the class of organic compounds known as acyl monophosphates. These are organic compounds containing a monophosphate linked to an acyl group. They have the general structure R-CO-P(O)(O)OH, R=H or organyl.
