ChemFOnt: Showing chemical card for 8,11,14-Eicosatrienoic acid (CFc000336965)

Record Information

Version

1.0

Creation Date

Update Date

2022-09-14 05:30:25 UTC

Chemfont ID

CFc000336965

Molecule Identification

Common Name

8,11,14-Eicosatrienoic acid

Definition

8,11,14-Eicosatrienoic acid is a 20-carbon-chain omega-6 fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid (5,8,11,14-eicosatetraenoic acid) only at position 5. 8,11,14-Eicosatrienoic acid is also known as Dihomo-gamma-linolenic acid (DGLA). In physiological literature, it is given the name 20:3(n-6). DGLA is the elongation product of the 18 carbon gamma-linolenic acid (GLA). DGLA can be converted into prostaglandin E1 (PGE1). PGE1 inhibits platelet aggregation and also exerts a vasodilatory effect. DGLA competes with arachadonic acid for COX and lipoxygenase, inhibiting the production of arachadonic acid's eicosanoids [HMDB]

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
8,11,14-Eicosatrienoate	Generator

Chemical Formula

C₂₀H₃₄O₂

Average Molecular Weight

306.4828

Monoisotopic Molecular Weight

306.255880332

IUPAC Name

icosa-8,11,14-trienoic acid

Traditional Name

dihomo-gamma-linolenic acid

CAS Registry Number

1783-84-2

SMILES

CCCCCC=CCC=CCC=CCCCCCCC(O)=O

InChI Identifier

InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)

InChI Key

HOBAELRKJCKHQD-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as long-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Fatty Acyls

Sub Class

Fatty acids and conjugates

Direct Parent

Long-chain fatty acids

Alternative Parents

Substituents

Long-chain fatty acid
Unsaturated fatty acid
Straight chain fatty acid
Monocarboxylic acid or derivatives
Carboxylic acid
Carboxylic acid derivative
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Carbonyl group
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Exogenous (HMDB: HMDB02925)

Food

Milk and milk product

Unfermented milk

Milk (Cow) (FooDB: FOOD00618)

Process

Naturally occurring process

Biological process

Biochemical pathway

Metabolic pathway

Alpha Linolenic Acid and Linoleic Acid Metabolism (HMDB: HMDB02925)

Role

Not Available

Physical Properties

Predicted Properties

Property	Value	Source
Water Solubility	7.7e-05 g/L	ALOGPS
logP	7.24	ALOGPS
logP	6.95	ChemAxon
logS	-6.6	ALOGPS
pKa (Strongest Acidic)	4.89	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	37.3 Å²	ChemAxon
Rotatable Bond Count	15	ChemAxon
Refractivity	98.84 m³·mol⁻¹	ChemAxon
Polarizability	38.63 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0247333

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB023082

KNApSAcK ID

Not Available

Chemspider ID

2904

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

3011

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

Showing chemical card for 8,11,14-Eicosatrienoic acid (CFc000336965)

MOL for CFc000336965 (8,11,14-Eicosatrienoic acid)

3D MOL for CFc000336965 (8,11,14-Eicosatrienoic acid)

3D SDF for CFc000336965 (8,11,14-Eicosatrienoic acid)

3D-SDF for CFc000336965 (8,11,14-Eicosatrienoic acid)

PDB for CFc000336965 (8,11,14-Eicosatrienoic acid)

3D PDB for CFc000336965 (8,11,14-Eicosatrienoic acid)

SMILES for CFc000336965 (8,11,14-Eicosatrienoic acid)

INCHI for CFc000336965 (8,11,14-Eicosatrienoic acid)

Structure for CFc000336965 (8,11,14-Eicosatrienoic acid)

3D Structure for CFc000336965 (8,11,14-Eicosatrienoic acid)