Showing chemical card for 1-(3,4-Dihydroxyphenyl)-1,2-ethanediol (CFc000335778)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:28:32 UTC
Chemfont ID
CFc000335778
Molecule Identification
Common Name
1-(3,4-Dihydroxyphenyl)-1,2-ethanediol
Definition
3,4-dihydroxyphenylglycol, also known as beta,3,4-trihydroxy phenethyl alcohol or dhpg, is a member of the class of compounds known as catechols. Catechols are compounds containing a 1,2-benzenediol moiety. 3,4-dihydroxyphenylglycol is soluble (in water) and a very weakly acidic compound (based on its pKa). 3,4-dihydroxyphenylglycol can be found in olive, which makes 3,4-dihydroxyphenylglycol a potential biomarker for the consumption of this food product. 3,4-dihydroxyphenylglycol can be found primarily in blood, cerebrospinal fluid (CSF), and urine, as well as throughout most human tissues. 3,4-dihydroxyphenylglycol exists in all living organisms, ranging from bacteria to humans. In humans, 3,4-dihydroxyphenylglycol is involved in a couple of metabolic pathways, which include disulfiram action pathway and tyrosine metabolism. 3,4-dihydroxyphenylglycol is also involved in several metabolic disorders, some of which include tyrosinemia, transient, of the newborn, hawkinsinuria, dopamine beta-hydroxylase deficiency, and alkaptonuria. Moreover, 3,4-dihydroxyphenylglycol is found to be associated with menkes disease.
