Showing chemical card for Maslic acid (CFc000334645)
Record Information
Version
1.0
Creation Date
Update Date
2022-09-14 05:26:40 UTC
Chemfont ID
CFc000334645
Molecule Identification
Common Name
Maslic acid
Definition
Malic acid, also known as malate or 2-hydroxysuccinic acid, belongs to beta hydroxy acids and derivatives class of compounds. Those are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom. Malic acid is soluble (in water) and a weakly acidic compound (based on its pKa). Malic acid can be synthesized from succinic acid. Malic acid is also a parent compound for other transformation products, including but not limited to, 3-(omega-methylthio)alkylmalic acid, 2-(omega-methylthio)alkylmalic acid, and 2-(p-coumaroyl)malic acid. Malic acid can be found in a number of food items such as red raspberry, mandarin orange (clementine, tangerine), german camomile, and parsley, which makes malic acid a potential biomarker for the consumption of these food products. Malic acid can be found primarily in most biofluids, including sweat, saliva, blood, and cerebrospinal fluid (CSF). Malic acid exists in all living organisms, ranging from bacteria to humans. In humans, malic acid is involved in several metabolic pathways, some of which include gluconeogenesis, glycogenosis, type IB, the oncogenic action of fumarate, and triosephosphate isomerase. Malic acid is also involved in few metabolic disorders, which include fructose-1,6-diphosphatase deficiency, glycogen storage disease type 1A (GSD1A) or von gierke disease, glycogenosis, type IA. von gierke disease, and phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1). Moreover, malic acid is found to be associated with schizophrenia. Malic acid is an organic compound with the molecular formula C4H6O5. It is a dicarboxylic acid that is made by all living organisms, contributes to the pleasantly sour taste of fruits, and is used as a food additive. Malic acid has two stereoisomeric forms (L- and D-enantiomers), though only the L-isomer exists naturally. The salts and esters of malic acid are known as malates. The malate anion is an intermediate in the citric acid cycle .
Belongs to the class of organic compounds known as beta hydroxy acids and derivatives. Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.
