Showing chemical card for Acetyl sulfisoxazole (CFc000328720)
| Record Information | |
|---|---|
| Version | 1.0 |
| Creation Date | 2022-09-06 19:45:53 UTC |
| Update Date | 2022-09-14 05:04:21 UTC |
| Chemfont ID | CFc000328720 |
| Molecule Identification | |
| Common Name | Acetyl sulfisoxazole |
| Definition | Sulfisoxazole acetyl is an ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, _dihydropteroate synthase_, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, resulting in cell growth arrest and cell death [L2788]. It is often combined with erythromycin to treat acute otitis media caused by the bacteria, haemophilus influenzae [L2790]. |
| Structure |  |
| Synonyms | Not Available |
| Chemical Formula | |
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| IUPAC Name | |
| Traditional Name | |
| CAS Registry Number | 80-74-0 |
| SMILES | Not Available |
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| Chemical Taxonomy | |
| Classification | Not classified |
| Functional Ontology | |
| Physiological effect | Not Available |
| Disposition | |
| Process | Not Available |
| Role | Not Available |
| Physical Properties | |
| Predicted Properties | Not Available |
| External Links | |
| External Links | Not Available |
| References | |
| Synthesis Reference | Not Available |