Showing chemical card for Dichloroacetic acid (CFc000326058)
| Record Information | |
|---|---|
| Version | 1.0 |
| Creation Date | 2022-09-06 19:45:53 UTC |
| Update Date | 2022-09-14 04:59:18 UTC |
| Chemfont ID | CFc000326058 |
| Molecule Identification | |
| Common Name | Dichloroacetic acid |
| Definition | Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms. Salts of DCA are used as drugs since they inhibit the enzyme pyruvate dehydrogenase kinase. Early reports of its activity against brain cancer cells led patients to treat themselves with DCA, which is commercially available in non-pharmaceutical grade. A phase 1 study in 5 patients concluded that DCA was safe, but wasn't designed to establish effectiveness. DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization and removal of a wide variety of skin and tissue lesions), but was cancelled post market. |
| Structure |  |
| Synonyms | Not Available |
| Chemical Formula | |
| Average Molecular Weight | |
| Monoisotopic Molecular Weight | |
| IUPAC Name | |
| Traditional Name | |
| CAS Registry Number | 79-43-6 |
| SMILES | Not Available |
| InChI Identifier | |
| InChI Key | |
| Chemical Taxonomy | |
| Classification | Not classified |
| Functional Ontology | |
| Physiological effect | Not Available |
| Disposition | Biological location
|
| Process | Not Available |
| Role | Not Available |
| Physical Properties | |
| Predicted Properties | Not Available |
| External Links | |
| External Links | Not Available |
| References | |
| Synthesis Reference | Not Available |