ChemFOnt: Showing chemical card for Chlorotoxin I-131 (CFc000323714)

Record Information
Version	1.0
Creation Date	2022-09-06 19:45:53 UTC
Update Date	2022-09-14 04:54:52 UTC
Chemfont ID	CFc000323714
Molecule Identification
Common Name	Chlorotoxin I-131
Definition	Chlorotoxin I-131 is investigated in clinical trials for treating brain cancer. Chlorotoxin I-131 binds to and reduces the activity of a matrix metalloproteinase (MMP) that regulates functioning of the chloride channels on cell membranes. Chlorotoxin is a small 36-amino-acid peptide that selectively binds to glioma cells but not normal brain parenchyma. It is a synthetic version of a neurotoxin isolated from the venom of the Giant Yellow Israeli scorpion Leiurus quinquestriatus. The synthetic version of this peptide has been manufactured and covalently linked to iodine 131 as a means of targeting radiation to tumor cells in the treatment of brain cancer. The selective effects of Chlorotoxin I-131 are regulated by its action on MMP2 receptors.
Structure	MOL SDF PDB SMILES InChI MOL for CFc000323714 (Chlorotoxin I-131) Not Available 3D MOL for CFc000323714 (Chlorotoxin I-131) Not Available 3D SDF for CFc000323714 (Chlorotoxin I-131) Not Available 3D-SDF for CFc000323714 (Chlorotoxin I-131) Not Available PDB for CFc000323714 (Chlorotoxin I-131) Not Available 3D PDB for CFc000323714 (Chlorotoxin I-131) Not Available SMILES for CFc000323714 (Chlorotoxin I-131) Not Available INCHI for CFc000323714 (Chlorotoxin I-131) Not Available Structure for CFc000323714 (Chlorotoxin I-131) 3D Structure for CFc000323714 (Chlorotoxin I-131) Not Available
Synonyms	Not Available
Chemical Formula
Average Molecular Weight
Monoisotopic Molecular Weight
IUPAC Name
Traditional Name
CAS Registry Number	Not Available
SMILES	Not Available
InChI Identifier
InChI Key
Chemical Taxonomy
Classification	Not classified
Functional Ontology
Physiological effect	Not Available
Disposition	Source Exogenous Exogenous (DrugBank: DB05462)
Process	Not Available
Role	Not Available
Physical Properties
Predicted Properties	Not Available
External Links
External Links	Not Available
References
Synthesis Reference	Not Available

Showing chemical card for Chlorotoxin I-131 (CFc000323714)

MOL for CFc000323714 (Chlorotoxin I-131)

3D MOL for CFc000323714 (Chlorotoxin I-131)

3D SDF for CFc000323714 (Chlorotoxin I-131)

3D-SDF for CFc000323714 (Chlorotoxin I-131)

PDB for CFc000323714 (Chlorotoxin I-131)

3D PDB for CFc000323714 (Chlorotoxin I-131)

SMILES for CFc000323714 (Chlorotoxin I-131)

INCHI for CFc000323714 (Chlorotoxin I-131)

Structure for CFc000323714 (Chlorotoxin I-131)

3D Structure for CFc000323714 (Chlorotoxin I-131)