Showing chemical card for (6R)-Folinic acid (CFc000226754)
Record Information
Version
1.0
Creation Date
2022-08-28 10:25:12 UTC
Update Date
2022-09-14 01:51:16 UTC
Chemfont ID
CFc000226754
Molecule Identification
Common Name
(6R)-Folinic acid
Definition
N5-Formyl-THF, also known as leucovorin or rescuvolin, belongs to the class of organic compounds known as tetrahydrofolic acids. These are heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with at least one L-glutamic acid unit. N5-Formyl-THF exists in all living species, ranging from bacteria to plants to humans. In humans, N5-formyl-THF is involved in the metabolic disorder called the methylenetetrahydrofolate reductase deficiency (mthfrd) pathway. N5-Formyl-THF is found, on average, in the highest concentration within lettuces (Lactuca sativa). This could make N5-formyl-THF a potential biomarker for the consumption of these foods. N5-Formyl-THF is a primary metabolite. Primary metabolites are metabolically or physiologically essential metabolites. They are directly involved in an organism’s growth, development or reproduction. Based on a literature review very few articles have been published on N5-Formyl-THF.
Belongs to the class of organic compounds known as tetrahydrofolic acids. These are heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with at least one L-glutamic acid unit.
