ChemFOnt: Showing chemical card for 3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid (CFc000122500)

Record Information

Version

1.0

Creation Date

2022-08-28 10:25:12 UTC

Update Date

2022-09-13 21:47:43 UTC

Chemfont ID

CFc000122500

Molecule Identification

Common Name

3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid

Definition

3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 3-(2,3,4-trimethoxyphenyl)propanoic acid. It is generated by UDP-glucuronosyltransferase 1-1 (P22309) enzyme via an aliphatic-acyl-O-glucuronidation reaction. This aliphatic-acyl-O-glucuronidation occurs in humans.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
3,4,5-Trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylate	Generator

Chemical Formula

C₁₈H₂₄O₁₁

Average Molecular Weight

416.379

Monoisotopic Molecular Weight

416.131861593

IUPAC Name

3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid

Traditional Name

3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid

CAS Registry Number

Not Available

SMILES

COC1=C(OC)C(OC)=C(CCC(=O)OC2OC(C(O)C(O)C2O)C(O)=O)C=C1

InChI Identifier

InChI=1S/C18H24O11/c1-25-9-6-4-8(14(26-2)15(9)27-3)5-7-10(19)28-18-13(22)11(20)12(21)16(29-18)17(23)24/h4,6,11-13,16,18,20-22H,5,7H2,1-3H3,(H,23,24)

InChI Key

CSPUQVSDBHPCIG-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as o-glucuronides. These are glucuronides in which the aglycone is linked to the carbohydrate unit through an O-glycosidic bond.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbohydrates and carbohydrate conjugates

Direct Parent

O-glucuronides

Alternative Parents

Substituents

1-o-glucuronide
O-glucuronide
Phenoxy compound
Anisole
Methoxybenzene
Phenol ether
Alkyl aryl ether
Beta-hydroxy acid
Fatty acid ester
Pyran
Dicarboxylic acid or derivatives
Benzenoid
Oxane
Fatty acyl
Monocyclic benzene moiety
Monosaccharide
Hydroxy acid
Carboxylic acid ester
Secondary alcohol
Carboxylic acid
Acetal
Carboxylic acid derivative
Organoheterocyclic compound
Oxacycle
Ether
Polyol
Alcohol
Carbonyl group
Hydrocarbon derivative
Organic oxide
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Endogenous (HMDB: HMDB0142091)

Process

Not Available

Role

Not Available

Physical Properties

Predicted Properties

Property	Value	Source
Water Solubility	2.9 g/L	ALOGPS
logP	-0.06	ALOGPS
logP	-0.37	ChemAxon
logS	-2.2	ALOGPS
pKa (Strongest Acidic)	3.13	ChemAxon
pKa (Strongest Basic)	-3.7	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	161.21 Å²	ChemAxon
Rotatable Bond Count	9	ChemAxon
Refractivity	93.65 m³·mol⁻¹	ChemAxon
Polarizability	40.62 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0142091

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

Showing chemical card for 3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid (CFc000122500)

MOL for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

3D MOL for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

3D SDF for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

3D-SDF for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

PDB for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

3D PDB for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

SMILES for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

INCHI for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

Structure for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)

3D Structure for CFc000122500 (3,4,5-trihydroxy-6-{[3-(2,3,4-trimethoxyphenyl)propanoyl]oxy}oxane-2-carboxylic acid)