ChemFOnt: Showing chemical card for 6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid (CFc000120103)

Record Information

Version

1.0

Creation Date

2022-08-28 10:25:12 UTC

Update Date

2022-09-13 21:44:05 UTC

Chemfont ID

CFc000120103

Molecule Identification

Common Name

6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid

Definition

6-(4-{2-[(4-aminobutyl)-c-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of n-(4-aminobutyl)-3-hydroxy-3-(4-hydroxy-3,5-dimethoxyphenyl)propanimidic acid. It is generated by UDP-glucuronosyltransferase 1-1 (P22309) enzyme via an aromatic-OH-glucuronidation reaction. This aromatic-OH-glucuronidation occurs in humans.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylate	Generator

Chemical Formula

C₂₁H₃₂N₂O₁₁

Average Molecular Weight

488.49

Monoisotopic Molecular Weight

488.200609858

IUPAC Name

6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid

Traditional Name

6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid

CAS Registry Number

Not Available

SMILES

COC1=CC(=CC(OC)=C1OC1OC(C(O)C(O)C1O)C(O)=O)C(O)CC(O)=NCCCCN

InChI Identifier

InChI=1S/C21H32N2O11/c1-31-12-7-10(11(24)9-14(25)23-6-4-3-5-22)8-13(32-2)18(12)33-21-17(28)15(26)16(27)19(34-21)20(29)30/h7-8,11,15-17,19,21,24,26-28H,3-6,9,22H2,1-2H3,(H,23,25)(H,29,30)

InChI Key

BJKJOGUGXRNXHL-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as phenolic glycosides. These are organic compounds containing a phenolic structure attached to a glycosyl moiety. Some examples of phenolic structures include lignans, and flavonoids. Among the sugar units found in natural glycosides are D-glucose, L-Fructose, and L rhamnose.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbohydrates and carbohydrate conjugates

Direct Parent

Phenolic glycosides

Alternative Parents

Substituents

Phenolic glycoside
O-glucuronide
1-o-glucuronide
Glucuronic acid or derivatives
Hexose monosaccharide
O-glycosyl compound
M-dimethoxybenzene
Dimethoxybenzene
Phenoxy compound
Anisole
Phenol ether
Methoxybenzene
Alkyl aryl ether
Beta-hydroxy acid
Oxane
Monocyclic benzene moiety
Hydroxy acid
Benzenoid
Monosaccharide
Pyran
Secondary alcohol
Amino acid
Amino acid or derivatives
Acetal
Oxacycle
Carboximidic acid
Carboximidic acid derivative
Carboxylic acid derivative
Carboxylic acid
Ether
Organoheterocyclic compound
Organic 1,3-dipolar compound
Propargyl-type 1,3-dipolar organic compound
Monocarboxylic acid or derivatives
Polyol
Organopnictogen compound
Organic oxide
Hydrocarbon derivative
Alcohol
Carbonyl group
Primary aliphatic amine
Organic nitrogen compound
Aromatic alcohol
Primary amine
Amine
Organonitrogen compound
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Endogenous (HMDB: HMDB0139694)

Process

Not Available

Role

Not Available

Physical Properties

Predicted Properties

Property	Value	Source
Water Solubility	1.5 g/L	ALOGPS
logP	-2.2	ALOGPS
logP	-4.8	ChemAxon
logS	-2.5	ALOGPS
pKa (Strongest Acidic)	2.66	ChemAxon
pKa (Strongest Basic)	10.2	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	13	ChemAxon
Hydrogen Donor Count	7	ChemAxon
Polar Surface Area	213.75 Å²	ChemAxon
Rotatable Bond Count	12	ChemAxon
Refractivity	114.95 m³·mol⁻¹	ChemAxon
Polarizability	48.99 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0139694

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

Showing chemical card for 6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid (CFc000120103)

MOL for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

3D MOL for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

3D SDF for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

3D-SDF for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

PDB for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

3D PDB for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

SMILES for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

INCHI for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

Structure for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)

3D Structure for CFc000120103 (6-(4-{2-[(4-aminobutyl)-C-hydroxycarbonimidoyl]-1-hydroxyethyl}-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid)