ChemFOnt: Showing chemical card for 3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid (CFc000114307)

Record Information

Version

1.0

Creation Date

2022-08-28 10:25:12 UTC

Update Date

2022-09-13 21:35:22 UTC

Chemfont ID

CFc000114307

Molecule Identification

Common Name

3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid

Definition

3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 2-(2,5-dihydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one. It is generated by UDP-glucuronosyltransferase 1-1 (P22309) enzyme via an aromatic-OH-glucuronidation reaction. This aromatic-OH-glucuronidation occurs in humans.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
3,4,5-Trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylate	Generator

Chemical Formula

C₂₂H₂₄O₁₃

Average Molecular Weight

496.421

Monoisotopic Molecular Weight

496.121690833

IUPAC Name

3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid

Traditional Name

3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid

CAS Registry Number

None

SMILES

COC1=C(O)C=C(C(C)C(=O)C2=C(O)C=C(O)C=C2O)C(OC2OC(C(O)C(O)C2O)C(O)=O)=C1

InChI Identifier

InChI=1S/C22H24O13/c1-7(16(27)15-11(25)3-8(23)4-12(15)26)9-5-10(24)14(33-2)6-13(9)34-22-19(30)17(28)18(29)20(35-22)21(31)32/h3-7,17-20,22-26,28-30H,1-2H3,(H,31,32)

InChI Key

GLLRIHBPYMXVDT-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as stilbene glycosides. Stilbene glycosides are compounds structurally characterized by the presence of a carbohydrate moiety glycosidically linked to the stilbene skeleton.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Stilbenes

Sub Class

Stilbene glycosides

Direct Parent

Stilbene glycosides

Alternative Parents

Substituents

Stilbene glycoside
Alpha-methyldeoxybenzoin flavonoid
Phenolic glycoside
1-o-glucuronide
O-glucuronide
Glucuronic acid or derivatives
Alkyl-phenylketone
Glycosyl compound
O-glycosyl compound
Acylphloroglucinol derivative
Methoxyphenol
Phenylketone
4-alkoxyphenol
Benzenetriol
Phloroglucinol derivative
Phenylpropane
Anisole
Methoxybenzene
Aryl alkyl ketone
Aryl ketone
Phenoxy compound
Benzoyl
Phenol ether
Alkyl aryl ether
Beta-hydroxy acid
1-hydroxy-4-unsubstituted benzenoid
1-hydroxy-2-unsubstituted benzenoid
Phenol
Hydroxy acid
Monosaccharide
Monocyclic benzene moiety
Benzenoid
Oxane
Pyran
Vinylogous acid
Ketone
Secondary alcohol
Acetal
Oxacycle
Organoheterocyclic compound
Polyol
Monocarboxylic acid or derivatives
Carboxylic acid derivative
Carboxylic acid
Ether
Organic oxide
Organooxygen compound
Hydrocarbon derivative
Carbonyl group
Organic oxygen compound
Alcohol
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Endogenous (HMDB: HMDB0133898)

Plant

Plant (HMDB: HMDB0133898)

Process

Not Available

Role

Not Available

Physical Properties

Predicted Properties

Property	Value	Source
Water Solubility	1.8 g/L	ALOGPS
logP	1.43	ALOGPS
logP	1.58	ChemAxon
logS	-2.4	ALOGPS
pKa (Strongest Acidic)	2.87	ChemAxon
pKa (Strongest Basic)	-3.7	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	13	ChemAxon
Hydrogen Donor Count	8	ChemAxon
Polar Surface Area	223.67 Å²	ChemAxon
Rotatable Bond Count	7	ChemAxon
Refractivity	114.14 m³·mol⁻¹	ChemAxon
Polarizability	46.2 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

HMDB0133898

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB090925

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

131837703

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

Showing chemical card for 3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid (CFc000114307)

MOL for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

3D MOL for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

3D SDF for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

3D-SDF for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

PDB for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

3D PDB for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

SMILES for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

INCHI for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

Structure for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)

3D Structure for CFc000114307 (3,4,5-trihydroxy-6-{4-hydroxy-5-methoxy-2-[1-oxo-1-(2,4,6-trihydroxyphenyl)propan-2-yl]phenoxy}oxane-2-carboxylic acid)