ChemFOnt: Showing chemical card for 3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid (CFc000105294)

Record Information

Version

1.0

Creation Date

2022-08-28 10:25:12 UTC

Update Date

2022-09-13 21:22:10 UTC

Chemfont ID

CFc000105294

Molecule Identification

Common Name

3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid

Definition

3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 3-(3,4,5-trimethoxyphenyl)prop-2-enoic acid. It is generated by UDP-glucuronosyltransferase 1-1 (P22309) enzyme via an aliphatic-acyl-O-glucuronidation reaction. This aliphatic-acyl-O-glucuronidation occurs in humans.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
3,4,5-Trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylate	Generator

Chemical Formula

C₁₈H₂₂O₁₁

Average Molecular Weight

414.363

Monoisotopic Molecular Weight

414.116211528

IUPAC Name

3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid

Traditional Name

3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid

CAS Registry Number

None

SMILES

COC1=CC(C=CC(=O)OC2OC(C(O)C(O)C2O)C(O)=O)=CC(OC)=C1OC

InChI Identifier

InChI=1S/C18H22O11/c1-25-9-6-8(7-10(26-2)15(9)27-3)4-5-11(19)28-18-14(22)12(20)13(21)16(29-18)17(23)24/h4-7,12-14,16,18,20-22H,1-3H3,(H,23,24)

InChI Key

KSLYXBOFIRPLJD-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as o-cinnamoyl glycosides. These are o-glycoside derivatives of cinnamic acid. Cinnamic acid is an aromatic compound containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid.

Kingdom

Organic compounds

Super Class

Phenylpropanoids and polyketides

Class

Cinnamic acids and derivatives

Sub Class

Cinnamic acid esters

Direct Parent

O-cinnamoyl glycosides

Alternative Parents

Substituents

O-cinnamoyl glycoside
1-o-glucuronide
O-glucuronide
Glucuronic acid or derivatives
Coumaric acid or derivatives
Phenoxy compound
Anisole
Phenol ether
Methoxybenzene
Styrene
Alkyl aryl ether
Beta-hydroxy acid
Fatty acid ester
Fatty acyl
Pyran
Hydroxy acid
Monocyclic benzene moiety
Oxane
Benzenoid
Dicarboxylic acid or derivatives
Monosaccharide
Alpha,beta-unsaturated carboxylic ester
Enoate ester
Secondary alcohol
Carboxylic acid ester
Ether
Acetal
Organoheterocyclic compound
Carboxylic acid
Carboxylic acid derivative
Oxacycle
Polyol
Alcohol
Carbonyl group
Hydrocarbon derivative
Organic oxide
Organic oxygen compound
Organooxygen compound
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

Not Available

Functional Ontology

Not Available

Endogenous (HMDB: HMDB0124885)

Plant

Plant (HMDB: HMDB0124885)

Process

Not Available

Role

Not Available

Physical Properties

Predicted Properties

Property	Value	Source
Water Solubility	1.87 g/L	ALOGPS
logP	0.16	ALOGPS
logP	-0.051	ChemAxon
logS	-2.3	ALOGPS
pKa (Strongest Acidic)	3.14	ChemAxon
pKa (Strongest Basic)	-3.7	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	10	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	161.21 Å²	ChemAxon
Rotatable Bond Count	8	ChemAxon
Refractivity	94.75 m³·mol⁻¹	ChemAxon
Polarizability	40.42 Å³	ChemAxon
Number of Rings	2	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0124885

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB083806

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

Showing chemical card for 3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid (CFc000105294)

MOL for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

3D MOL for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

3D SDF for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

3D-SDF for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

PDB for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

3D PDB for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

SMILES for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

INCHI for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

Structure for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)

3D Structure for CFc000105294 (3,4,5-trihydroxy-6-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}oxane-2-carboxylic acid)