ChemFOnt: Showing chemical card for 18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid (CFc000042714)

Record Information

Version

1.0

Creation Date

2022-08-28 10:25:12 UTC

Update Date

2022-09-13 19:45:22 UTC

Chemfont ID

CFc000042714

Molecule Identification

Common Name

18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Definition

18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid is an eicosanoid lipid molecule. It is classified as a member of the hydroxyeicosatetraenoic acids. Hydroxyeicosatetraenoic acids are eicosanoic acids with an attached hydroxyl group and four CC double bonds. 18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid is considered to be practically insoluble (in water) and acidic.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
(5Z,8Z,11Z,14Z)-18-Hydroxy-5,8,11,14-eicosatetraenoic acid	ChEBI
(5Z,8Z,11Z,14Z)-18-Hydroxyeicosa-5,8,11,14-tetraenoic acid	ChEBI
(5Z,8Z,11Z,14Z)-18-Hydroxyicosa-5,8,11,14-tetraenoic acid	ChEBI
(Z,Z,Z,Z)-18-Hydroxy-5,8,11,14-eicosatetraenoic acid	ChEBI
(Z,Z,Z,Z)-18-Hydroxy-5,8,11,14-icosatetraenoic acid	ChEBI
18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid	ChEBI
(5Z,8Z,11Z,14Z)-18-Hydroxy-5,8,11,14-eicosatetraenoate	Generator
(5Z,8Z,11Z,14Z)-18-Hydroxyeicosa-5,8,11,14-tetraenoate	Generator
(5Z,8Z,11Z,14Z)-18-Hydroxyicosa-5,8,11,14-tetraenoate	Generator
(Z,Z,Z,Z)-18-Hydroxy-5,8,11,14-eicosatetraenoate	Generator
(Z,Z,Z,Z)-18-Hydroxy-5,8,11,14-icosatetraenoate	Generator
18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoate	Generator
18-Hydroxy-5,8,11,14-eicosatetraenoic acid	HMDB
18-Hydroxyeicosatetraenoic acid	HMDB
18-Hydroxyarachidonic acid	HMDB
18-HETE	HMDB

Chemical Formula

C₂₀H₃₂O₃

Average Molecular Weight

320.473

Monoisotopic Molecular Weight

320.23514489

IUPAC Name

(5Z,8Z,11Z,14Z)-18-hydroxyicosa-5,8,11,14-tetraenoic acid

Traditional Name

18-hete

CAS Registry Number

133268-58-3

SMILES

CCC(O)CC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O

InChI Identifier

InChI=1S/C20H32O3/c1-2-19(21)17-15-13-11-9-7-5-3-4-6-8-10-12-14-16-18-20(22)23/h4-7,10-13,19,21H,2-3,8-9,14-18H2,1H3,(H,22,23)/b6-4-,7-5-,12-10-,13-11-

InChI Key

PPCHNRUZQWLEMF-XBOCNYGYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as hydroxyeicosatetraenoic acids. These are eicosanoic acids with an attached hydroxyl group and four CC double bonds.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Fatty Acyls

Sub Class

Eicosanoids

Direct Parent

Hydroxyeicosatetraenoic acids

Alternative Parents

Substituents

Hydroxyeicosatetraenoic acid
Long-chain fatty acid
Hydroxy fatty acid
Fatty acid
Unsaturated fatty acid
Secondary alcohol
Carboxylic acid derivative
Carboxylic acid
Monocarboxylic acid or derivatives
Organic oxide
Organic oxygen compound
Alcohol
Hydrocarbon derivative
Carbonyl group
Organooxygen compound
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

HETE (CHEBI:63579 )
Hydroxy/hydroperoxyeicosatetraenoic acids (LMFA03060092 )

Functional Ontology

Not Available

Exogenous (HMDB: HMDB0062302)

Process

Not Available

Role

Not Available

Physical Properties

Predicted Properties

Property	Value	Source
Water Solubility	0.002 g/L	ALOGPS
logP	5.81	ALOGPS
logP	5.2	ChemAxon
logS	-5.2	ALOGPS
pKa (Strongest Acidic)	4.82	ChemAxon
pKa (Strongest Basic)	-1.3	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	57.53 Å²	ChemAxon
Rotatable Bond Count	14	ChemAxon
Refractivity	101.62 m³·mol⁻¹	ChemAxon
Polarizability	37.87 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	Yes	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

External Links

HMDB ID

HMDB0062302

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

Not Available

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

6442778

PDB ID

Not Available

ChEBI ID

63579

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

Showing chemical card for 18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid (CFc000042714)

MOL for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

3D MOL for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

3D SDF for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

3D-SDF for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

PDB for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

3D PDB for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

SMILES for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

INCHI for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

Structure for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)

3D Structure for CFc000042714 (18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid)