ChemFOnt: Showing chemical card for Ganglioside GQ1c (d18:1/20:0) (CFc000007517)

Record Information

Version

1.0

Creation Date

2022-08-28 10:25:12 UTC

Update Date

2022-09-13 18:53:52 UTC

Chemfont ID

CFc000007517

Molecule Identification

Common Name

Ganglioside GQ1c (d18:1/20:0)

Definition

3291

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value

Source

(2S,4S,5R)-2-{[(1S,2R)-1-[(3R,4S,6S)-6-carboxy-6-{[(1S,2R)-1-[(3R,4S,6S)-6-carboxy-6-{[(2R,3S,4R,5R,6S)-3-{[(2S,3R,4R,5R,6R)-4-{[(2R,3R,4S,5S,6R)-4-{[(2S,4S,5R)-2-carboxy-4-hydroxy-5-[(1-hydroxyethylidene)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-(2-oxopropyl)oxan-2-yl]oxy}-6-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-{[(2S,3R)-3-hydroxy-2-[(1-hydroxyicosylidene)amino]octadec-4-en-1-yl]oxy}-2-(hydroxymethyl)oxan-3-yl]oxy}-5-hydroxy-2-(hydroxymethyl)oxan-4-yl]oxy}-4-hydroxy-3-[(1-hydroxyethylidene)amino]oxan-2-yl]-1,3-dihydroxypropan-2-yl]oxy}-4-hydroxy-3-[(1-hydroxyethylidene)amino]oxan-2-yl]-1,3-dihydroxypropan-2-yl]oxy}-4-hydroxy-5-[(1-hydroxyethylidene)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate

HMDB

Chemical Formula

C₁₀₉H₁₈₇N₅O₅₅

Average Molecular Weight

2447.6516

Monoisotopic Molecular Weight

2446.198955219

IUPAC Name

(2S,4S,5R)-2-{[(2R,3R,4S,5S,6R)-2-{[(2S,3R,4R,5R,6R)-2-{[(2R,3S,4R,5R,6S)-4-{[(2S,4S,5R)-2-carboxy-6-[(1S,2R)-2-{[(2S,4S,5R)-2-carboxy-6-[(1S,2R)-2-{[(2S,4S,5R)-2-carboxy-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy}-1,3-dihydroxypropyl]-5-acetamido-4-hydroxyoxan-2-yl]oxy}-1,3-dihydroxypropyl]-5-acetamido-4-hydroxyoxan-2-yl]oxy}-6-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-{[(2S,3R,4E)-3-hydroxy-2-icosanamidooctadec-4-en-1-yl]oxy}-2-(hydroxymethyl)oxan-3-yl]oxy}-5-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-(2-oxopropyl)oxan-4-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid

Traditional Name

CAS Registry Number

None

SMILES

CCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@@]5(C[C@H](O)[C@@H](NC(C)=O)C(O5)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]4O)[C@H]3CC(C)=O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)C(O3)[C@H](O)[C@@H](CO)O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)C(O3)[C@H](O)[C@@H](CO)O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)C(O3)[C@H](O)[C@H](O)CO)C(O)=O)C(O)=O)C(O)=O)[C@H]2O)[C@H](O)[C@H]1O)[C@H](O)\C=C\CCCCCCCCCCCCC

InChI Identifier

InChI=1S/C109H187N5O55/c1-8-10-12-14-16-18-20-22-23-24-25-27-29-31-33-35-37-39-74(135)114-60(61(128)38-36-34-32-30-28-26-21-19-17-15-13-11-9-2)53-154-99-86(143)85(142)90(72(51-121)157-99)160-101-88(145)97(91(73(52-122)158-101)161-98-59(40-54(3)123)89(81(138)68(47-117)155-98)159-100-87(144)96(82(139)69(48-118)156-100)168-108(104(150)151)43-64(131)76(111-56(5)125)93(165-108)80(137)67(134)46-116)169-109(105(152)153)44-65(132)78(113-58(7)127)95(167-109)84(141)71(50-120)163-107(103(148)149)42-63(130)77(112-57(6)126)94(166-107)83(140)70(49-119)162-106(102(146)147)41-62(129)75(110-55(4)124)92(164-106)79(136)66(133)45-115/h36,38,59-73,75-101,115-122,128-134,136-145H,8-35,37,39-53H2,1-7H3,(H,110,124)(H,111,125)(H,112,126)(H,113,127)(H,114,135)(H,146,147)(H,148,149)(H,150,151)(H,152,153)/b38-36+/t59-,60+,61-,62+,63+,64+,65+,66-,67-,68-,69-,70-,71-,72-,73-,75-,76-,77-,78-,79-,80-,81+,82+,83-,84-,85-,86-,87-,88-,89-,90-,91+,92?,93?,94?,95?,96+,97-,98+,99-,100+,101+,106-,107-,108+,109+/m1/s1

InChI Key

RWEKXNHIQHNUFY-QYIRSSOTSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as gangliosides. These are lipid molecules composed of a glycosphingolipid (ceramide and saccharide) with one or more sialic acids linked on the sugar chain. They are usually oligoglycosylceramides derived from lactosylceramide and containing a sialic acid residue such as N-acetylneuraminic acid.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Sphingolipids

Sub Class

Glycosphingolipids

Direct Parent

Gangliosides

Alternative Parents

Substituents

Neuaca2-3galb1-4glcb-cer_backbone
Glycosyl-n-acylsphingosine
Oligosaccharide
N-acylneuraminic acid
N-acylneuraminic acid or derivatives
Neuraminic acid
Fatty acyl glycoside
C-glucuronide
Tetracarboxylic acid or derivatives
Alkyl glycoside
C-glycosyl compound
Glycosyl compound
O-glycosyl compound
Ketal
Fatty amide
N-acyl-amine
Oxane
Fatty acyl
Pyran
Acetamide
Ketone
Carboxamide group
Secondary alcohol
Secondary carboxylic acid amide
Acetal
Carboxylic acid derivative
Carboxylic acid
Oxacycle
Organoheterocyclic compound
Polyol
Hydrocarbon derivative
Alcohol
Organic oxide
Carbonyl group
Organic nitrogen compound
Organic oxygen compound
Primary alcohol
Organopnictogen compound
Organooxygen compound
Organonitrogen compound
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

Not Available

Functional Ontology

Physiological effect

Organoleptic effect

Touch

Smooth (HMDB: HMDB0011953)

Disposition

Biological location

Cellular substructure

Route of exposure

Enteral

Ingestion (HMDB: HMDB0011953)

Source

Endogenous

Endogenous (HMDB: HMDB0011953)

Animal

Animal (HMDB: HMDB0011953)

Exogenous

Food

Food (HMDB: HMDB0011953)

Animal origin

Poultry

Pheasant (FooDB: FOOD00430)
Squab (FooDB: FOOD00481)
Turkey (FooDB: FOOD00494)
Quail (FooDB: FOOD00541)
Anatidae (FooDB: FOOD00576)
Rock ptarmigan (FooDB: FOOD00597)
Columbidae (Dove, Pigeon) (FooDB: FOOD00610)
Chicken (FooDB: FOOD00329)
Mallard duck (FooDB: FOOD00353)
Emu (FooDB: FOOD00360)
Greylag goose (FooDB: FOOD00368)
Guinea hen (FooDB: FOOD00373)
Ostrich (FooDB: FOOD00422)
Velvet duck (FooDB: FOOD00427)

Lagomorph

Ovis

Sheep (Mutton, Lamb) (FooDB: FOOD00473)

Bovine

Venison

Deer (FooDB: FOOD00524)
Mule deer (FooDB: FOOD00348)
Elk (FooDB: FOOD00359)

Caprae

Domestic goat (FooDB: FOOD00529)

Swine

Domestic pig (FooDB: FOOD00536)
Wild boar (FooDB: FOOD00307)

Equine

Horse (FooDB: FOOD00378)

Exogenous (HMDB: HMDB0011953)

Process

Naturally occurring process

Biological process

Chemical reaction

Lipid Peroxidation (HMDB: HMDB0011953)

Biochemical pathway

Metabolic pathway

Fatty Acid Metabolism (HMDB: HMDB0011953)

Lipid metabolism pathway (HMDB: HMDB0011953)

Cellular process

Cell signaling (HMDB: HMDB0011953)

Biochemical process

Lipid transport (HMDB: HMDB0011953)

Role

Biological role

Membrane stabilizer (HMDB: HMDB0011953)

Molecular messenger

Signaling molecule (HMDB: HMDB0011953)

Industrial application

Food and nutrition

Food additive (HMDB: HMDB0011953)

Manufacturing industry

Material processing agent

Fluid processing agent

Surfactant

Surfactant (HMDB: HMDB0011953)

Physical Properties

Predicted Properties

Property	Value	Source
Water Solubility	1.67 g/L	ALOGPS
logP	0.46	ALOGPS
logP	-3.3	ChemAxon
logS	-3.2	ALOGPS
pKa (Strongest Acidic)	2.16	ChemAxon
pKa (Strongest Basic)	-3.9	ChemAxon
Physiological Charge	-4	ChemAxon
Hydrogen Acceptor Count	55	ChemAxon
Hydrogen Donor Count	34	ChemAxon
Polar Surface Area	965.2 Å²	ChemAxon
Rotatable Bond Count	76	ChemAxon
Refractivity	567.85 m³·mol⁻¹	ChemAxon
Polarizability	257.9 Å³	ChemAxon
Number of Rings	8	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

HMDB0011953

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB028622

KNApSAcK ID

Not Available

Chemspider ID

Not Available

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

53481229

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

Showing chemical card for Ganglioside GQ1c (d18:1/20:0) (CFc000007517)

MOL for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

3D MOL for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

3D SDF for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

3D-SDF for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

PDB for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

3D PDB for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

SMILES for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

INCHI for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

Structure for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))

3D Structure for CFc000007517 (Ganglioside GQ1c (d18:1/20:0))