ChemFOnt: Showing chemical card for Ganglioside GD1a (d18:0/12:0) (CFc000007341)

Record Information

Version

1.0

Creation Date

2022-08-28 10:25:12 UTC

Update Date

2022-09-13 18:53:37 UTC

Chemfont ID

CFc000007341

Molecule Identification

Common Name

Ganglioside GD1a (d18:0/12:0)

Definition

3291

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value

Source

(2S,4S,5R)-2-{[(2R,3R,4S,5S,6R)-2-{[(2S,3R,4R,5R,6R)-2-{[(2R,3S,4R,5R,6S)-4-{[(2S,4S,5R)-2-carboxy-4-hydroxy-5-[(1-hydroxyethylidene)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy}-6-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-6-{[(2S,3R)-3-hydroxy-2-[(1-hydroxydodecylidene)amino]octadecyl]oxy}-2-(hydroxymethyl)oxan-3-yl]oxy}-5-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-(2-oxopropyl)oxan-4-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4-hydroxy-5-[(1-hydroxyethylidene)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate

Generator, HMDB

Chemical Formula

C₇₉H₁₃₉N₃O₃₉

Average Molecular Weight

1754.9457

Monoisotopic Molecular Weight

1753.898571721

IUPAC Name

(2S,4S,5R)-2-{[(2R,3R,4S,5S,6R)-2-{[(2S,3R,4R,5R,6R)-2-{[(2R,3S,4R,5R,6S)-4-{[(2S,4S,5R)-2-carboxy-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy}-6-{[(2R,3S,4R,5R,6R)-6-{[(2S,3R)-2-dodecanamido-3-hydroxyoctadecyl]oxy}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-5-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-(2-oxopropyl)oxan-4-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-5-acetamido-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid

Traditional Name

CAS Registry Number

None

SMILES

CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@@]5(C[C@H](O)[C@@H](NC(C)=O)C(O5)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]4O)[C@H]3CC(C)=O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)C(O3)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]2O)[C@H](O)[C@H]1O)NC(=O)CCCCCCCCCCC

InChI Identifier

InChI=1S/C79H139N3O39/c1-6-8-10-12-14-16-17-18-19-21-22-24-26-28-45(92)44(82-54(97)29-27-25-23-20-15-13-11-9-7-2)39-110-73-62(103)61(102)66(52(37-87)113-73)116-75-64(105)71(121-79(77(108)109)32-47(94)56(81-42(5)91)69(119-79)58(99)49(96)34-84)67(53(38-88)114-75)117-72-43(30-40(3)89)65(59(100)50(35-85)111-72)115-74-63(104)70(60(101)51(36-86)112-74)120-78(76(106)107)31-46(93)55(80-41(4)90)68(118-78)57(98)48(95)33-83/h43-53,55-75,83-88,92-96,98-105H,6-39H2,1-5H3,(H,80,90)(H,81,91)(H,82,97)(H,106,107)(H,108,109)/t43-,44+,45-,46+,47+,48-,49-,50-,51-,52-,53-,55-,56-,57-,58-,59+,60+,61-,62-,63-,64-,65-,66-,67+,68?,69?,70+,71-,72+,73-,74+,75+,78+,79+/m1/s1

InChI Key

OPAYVKYRLBUPFG-QQIFVPJNSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as glycosphingolipids. These are sphingolipids containing a saccharide moiety glycosidically attached to the sphingoid base. Although saccharide moieties are mostly O-glycosidically linked to the ceramide moiety, other sphingolipids with glycosidic bonds of other types (e.G. S-,C-, or N-type) has been reported.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Sphingolipids

Sub Class

Glycosphingolipids

Direct Parent

Glycosphingolipids

Alternative Parents

Substituents

Glycosphingolipid
Oligosaccharide
N-acylneuraminic acid
N-acylneuraminic acid or derivatives
Neuraminic acid
Fatty acyl glycoside
C-glucuronide
Alkyl glycoside
O-glycosyl compound
C-glycosyl compound
Glycosyl compound
Ketal
Fatty acyl
Fatty amide
Dicarboxylic acid or derivatives
Pyran
N-acyl-amine
Oxane
Acetamide
Ketone
Secondary alcohol
Secondary carboxylic acid amide
Carboxamide group
Acetal
Carboxylic acid derivative
Carboxylic acid
Oxacycle
Organoheterocyclic compound
Polyol
Hydrocarbon derivative
Alcohol
Organic oxide
Carbonyl group
Organic nitrogen compound
Organic oxygen compound
Primary alcohol
Organopnictogen compound
Organooxygen compound
Organonitrogen compound
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

Not Available

Functional Ontology

Physiological effect

Organoleptic effect

Touch

Smooth (HMDB: HMDB0011777)

Disposition

Biological location

Cellular substructure

Route of exposure

Enteral

Ingestion (HMDB: HMDB0011777)

Source

Endogenous

Endogenous (HMDB: HMDB0011777)

Animal

Animal (HMDB: HMDB0011777)

Exogenous

Food

Food (HMDB: HMDB0011777)

Animal origin

Poultry

Pheasant (FooDB: FOOD00430)
Squab (FooDB: FOOD00481)
Turkey (FooDB: FOOD00494)
Quail (FooDB: FOOD00541)
Anatidae (FooDB: FOOD00576)
Rock ptarmigan (FooDB: FOOD00597)
Columbidae (Dove, Pigeon) (FooDB: FOOD00610)
Chicken (FooDB: FOOD00329)
Mallard duck (FooDB: FOOD00353)
Emu (FooDB: FOOD00360)
Greylag goose (FooDB: FOOD00368)
Guinea hen (FooDB: FOOD00373)
Ostrich (FooDB: FOOD00422)
Velvet duck (FooDB: FOOD00427)

Lagomorph

Ovis

Sheep (Mutton, Lamb) (FooDB: FOOD00473)

Bovine

Venison

Deer (FooDB: FOOD00524)
Mule deer (FooDB: FOOD00348)
Elk (FooDB: FOOD00359)

Caprae

Domestic goat (FooDB: FOOD00529)

Swine

Domestic pig (FooDB: FOOD00536)
Wild boar (FooDB: FOOD00307)

Equine

Horse (FooDB: FOOD00378)

Process

Naturally occurring process

Biological process

Chemical reaction

Lipid Peroxidation (HMDB: HMDB0011777)

Biochemical pathway

Metabolic pathway

Fatty Acid Metabolism (HMDB: HMDB0011777)

Lipid metabolism pathway (HMDB: HMDB0011777)

Cellular process

Cell signaling (HMDB: HMDB0011777)

Biochemical process

Lipid transport (HMDB: HMDB0011777)

Role

Biological role

Membrane stabilizer (HMDB: HMDB0011777)

Molecular messenger

Signaling molecule (HMDB: HMDB0011777)

Industrial application

Food and nutrition

Food additive (HMDB: HMDB0011777)

Manufacturing industry

Material processing agent

Fluid processing agent

Surfactant

Surfactant (HMDB: HMDB0011777)

Physical Properties

Predicted Properties

Property	Value	Source
Water Solubility	2.92 g/L	ALOGPS
logP	0.54	ALOGPS
logP	-1.9	ChemAxon
logS	-2.8	ALOGPS
pKa (Strongest Acidic)	2.54	ChemAxon
pKa (Strongest Basic)	-3.7	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	39	ChemAxon
Hydrogen Donor Count	24	ChemAxon
Polar Surface Area	674.1 Å²	ChemAxon
Rotatable Bond Count	55	ChemAxon
Refractivity	409.53 m³·mol⁻¹	ChemAxon
Polarizability	185.93 Å³	ChemAxon
Number of Rings	6	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

External Links

HMDB ID

HMDB0011777

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB028446

KNApSAcK ID

Not Available

Chemspider ID

35032092

KEGG Compound ID

Not Available

BioCyc ID

Not Available

BiGG ID

Not Available

Wikipedia Link

Not Available

METLIN ID

Not Available

PubChem Compound

53481053

PDB ID

Not Available

ChEBI ID

Not Available

Food Biomarker Ontology

Not Available

References

Synthesis Reference

Not Available

Showing chemical card for Ganglioside GD1a (d18:0/12:0) (CFc000007341)

MOL for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

3D MOL for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

3D SDF for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

3D-SDF for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

PDB for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

3D PDB for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

SMILES for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

INCHI for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

Structure for CFc000007341 (Ganglioside GD1a (d18:0/12:0))

3D Structure for CFc000007341 (Ganglioside GD1a (d18:0/12:0))