Showing chemical card for N-Methylputrescine (CFc000001948)
Record Information
Version
1.0
Creation Date
2022-08-28 10:25:12 UTC
Update Date
2022-09-13 18:46:42 UTC
Chemfont ID
CFc000001948
Molecule Identification
Common Name
N-Methylputrescine
Definition
N-Methylputrescine is a byproduct of putrescine (a diamine), via methylation by putrescine N-methyltransferase (PMT; EC 2.1.1.53). N-methylputrescine is able to affect protein synthesis to a small extent in stimulated H-35 hepatoma cells, being an inhibitor of cellular insulin-induced ornithine decarboxylase activity. (PMID: 2051998 ). Putrescine is related to cadaverine (another polyamine). Both are produced by the breakdown of amino acids in living and dead organisms and both are toxic in large doses. Putrescine and cadaverine are largely responsible for the foul odor of putrefying flesh, but also contribute to the odor of such processes as bad breath and bacterial vaginosis. Putrescine is also found in semen. Putrescine attacks s-adenosyl methionine and converts it to spermidine. Spermidine in turn attacks another s-adenosyl methionine and converts it to spermine. Putrescine is synthesized in small quantities by healthy living cells by the action of ornithine decarboxylase. N-Methylputrescine is a microbial metabolite.
3D Structure for CFc000001948 (N-Methylputrescine)
Synonyms
Value
Source
1-Amino-4-methylaminobutane
HMDB
N-Methyl-1,4-butanediamine
HMDB
N-Methyl-1,4-diaminobutane
HMDB
N-Methylbutane-1,4-diamine
HMDB
N-Methylputrescinium
HMDB
N1-Methyl-1,4-butanediamine
HMDB
Chemical Formula
C5H14N2
Average Molecular Weight
102.1781
Monoisotopic Molecular Weight
102.115698458
IUPAC Name
(4-aminobutyl)(methyl)amine
Traditional Name
N-methylputrescine
CAS Registry Number
14475-60-6
SMILES
CNCCCCN
InChI Identifier
InChI=1S/C5H14N2/c1-7-5-3-2-4-6/h7H,2-6H2,1H3
InChI Key
RMIVMBYMDISYFZ-UHFFFAOYSA-N
Chemical Taxonomy
Description
Belongs to the class of organic compounds known as dialkylamines. These are organic compounds containing a dialkylamine group, characterized by two alkyl groups bonded to the amino nitrogen.
